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Parcourir par sujet "Chronic kidney disease"

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    • Epigenetic Mechanisms and Kidney Diseases 

      Liakopoulos, V.; Georgianos, P. I.; Eleftheriadis, T.; Sarafidis, P. A. (2011)
      In recent years, molecular research has brought to light a series of mechanisms involved in the regulation of gene function without altering the DNA sequence. These mechanisms are described with the term "epigenetics" and ...

    • Evidence of blood and muscle redox status imbalance in experimentally induced renal insufficiency in a rabbit model 

      Poulianiti K.P., Karioti A., Kaltsatou A., Mitrou G.I., Koutedakis Y., Tepetes K., Christodoulidis G., Giakas G., Maridaki M.D., Stefanidis I., Jamurtas A.Z., Sakkas G.K., Karatzaferi C. (2019)
      Chronic kidney disease (CKD) is accompanied by a disturbed redox homeostasis, especially in end-stage patients, which is associated with pathological complications such as anemia, atherosclerosis, and muscle atrophy. ...

    • Evidence of functional deficits at the single muscle fiber level in experimentally-induced renal insufficiency 

      Mitrou G.I., Sakkas G.K., Poulianiti K.P., Karioti A., Tepetes K., Christodoulidis G., Giakas G., Stefanidis I., Geeves M.A., Koutedakis Y., Karatzaferi C. (2019)
      Chronic kidney disease patients present with metabolic and functional muscle abnormalities, called uremic myopathy, whose mechanisms have not yet been fully elucidated. We investigated whether chronic renal insufficiency ...

    • Hyperuricemia and chronic kidney disease: an enigma yet to be solved 

      Dousdampanis, P.; Trigka, K.; Musso, C. G.; Fourtounas, C. (2014)
      The role of uric acid (UA) on the pathogenesis and progression of chronic kidney disease (CKD) remains controversial. Experimental and clinical studies indicate that UA is associated with several risk factors of CKD including ...

    • Restless legs syndrome in hemodialysis patients: an epidemiologic survey in Greece 

      Stefanidis, I.; Vainas, A.; Dardiotis, E.; Giannaki, C. D.; Gourli, P.; Papadopoulou, D.; Vakianis, P.; Patsidis, E.; Eleftheriadis, T.; Liakopoulos, V.; Pournaras, S.; Sakkas, G. K.; Zintzaras, E.; Hadjigeorgiou, G. M. (2013)
      Background: Restless legs syndrome (RLS) is a sensorimotor disorder characterized by an uncontrolled need to move extremities accompanied by unpleasant sensations, which frequently leads to sleep disturbances. In hemodialysis ...

    • Systemic Redox Imbalance in Chronic Kidney Disease: A Systematic Review 

      Poulianiti K.P., Kaltsatou A., Mitrou G.I., Jamurtas A.Z., Koutedakis Y., Maridaki M., Stefanidis I., Sakkas G.K., Karatzaferi C. (2016)
      Patients with chronic kidney disease (CKD) experience imbalance between oxygen reactive species (ROS) production and antioxidant defenses leading to cell and tissue damage. However, it remains unclear at which stage of ...